Stephen J. Shamp, MD MSEE

About Dr. Shamp

Doctor Stephen (Steve) Shamp is a board certified Radiation Oncologist. He received his Bachelor of Science in Electrical Engineering from the University of Notre Dame. He went on to receive his Masters of Science in Electrical Engineering (MSEE) from the University of South Florida with Phi Kappa Phi Honors. He then earned a Masters of Science in Physiology from the University of Cincinnati and was bestowed the Mark A Snowdon Award for outstanding academic achievements. He then obtained his Medical Doctorate (MD) from the University of Cincinnati College of Medicine where he graduated with Alpha Omega Alpha (AOA) honors. He completed his internship in Internal Medicine at Jewish Hospital of Cincinnati.  Doctor Shamp then completed his residency training in Radiation Oncology at Case Western University Hospitals Cleveland, where he served as Chief Resident and received the RSNA Roentgen Resident Research Award.  He is author and co-primary investigator of CASE1518 clinical trial of external beam radiation therapy combined with immunotherapy in non-small cell lung cancer, and has presented at numerous scientific conferences.

Doctor Shamp is married and lives with his wife and family in St. Petersburg, Florida. In his free time he enjoys traveling, hiking, biking, watersports, scuba diving, astronomy, photography, and working on his Jeep Wrangler.

Cancers Treated (click to see list)

Central Nervous System Malignancies

Anaplastic and low grade glioma
Metastatic Cancer to Brain and/or Spine

Head and Neck Malignancies

Squamous Cell Carcinoma
Oral Cavity
Salivary Gland Tumors

Skin Cancer

Basal Cell Carcinoma (BCC)
Squamous Cell Carcinoma (SCC)

Breast Cancer

Invasive ductal carcinioma (IDC)
Invasive lobular carcinoma (ILC)
Ductal carcinoma in situ (DCIS)

Thoracic Malignancies

Non-Small Cell Lung Cancer (NSCLC)
Small Cell Lung Cancer (SCLC)

Gastrointestinal Malignancies

Esopagheal Cancer
Gastric Cancer
Hepatocelular Carcinoma
Pancreatic Cancer
Rectal Cancer
Anal Cancer

Genitourinary Malignancies

Prostate cancer
Bladder cancer
Testicular cancer
Kidney Cancer

Gynecologic Malignancies

Cervical Cancer
Endometrial Cancer
Vulvar Cancer
Vaginal Cancer
Uterine Sarcoma


Hodgkin's Lymphoma
Diffuse Large B-Cell Lymphoma (DLBCL)
Follicular Lymphoma
Non-Hodgkin's Lymphoma

Soft Tissue Sarcoma

Palliative Radiation Therapy

Bone Metastases
Spine Metastases
Brain Metastases
Stereotactic Body Radiation Therapy (SBRT) for oligometastatic disease

Benign Diseases


Treatment Expertise

External Beam Radiation Therapy (EBRT)

External beam radiation uses a sophisticated radiation machine called a linear accelerator to deliver focused beams of radiation. This is an effective treatment for many types of cancer, and can be used alone or in combination with surgery and/or chemotherapy.

Intensity Modulated Radiation Therapy (IMRT)

Intensity Modulated Radiation Therapy (IMRT) is an advanced radiation delivery technique which utilizes multiple radiation beams or arcs to deliver highly conformal radiation to the target area while reducing radiation dose to uninvolved areas to reduce side effects and/or complications.

Image Guided Radiation Therapy (IGRT)

Image Guided Radiaiton Therapy (IGRT) is the use of routine imaging, such as Cone-beam CT (CBCT) or portal imaging. This imaging is typically obtained prior to delivering radiation therapy to improve the the accuracy of the treatment.

Stereotactic Radiosurgery (SRS)

Stereotactic Radiosurgery (SRS) is used for certain tumors of the central nervous system, and involves the pinpoint delivery of high dose radiation therapy. This can involve from one to five total treatments.

Stereotactic Body Radiation Therapy (SBRT)

Stereotactic Body Radiation Therapy (SBRT) involves delivering  between one to five doses of  high dose radiation therapy with extreme accuracy.  This is commonly used for Stage I lung cancer, as well as certain other cancers.


Brachytherapy is the delivery of sealed radioactive sources directly inside or next to the area requiring treatment. I offer both high dose rate (HDR) and low dose rate (LDR) brachytherapy, for the treatment of certain prostate, cervical, endometrial, and skin cancers.


Clinical Trials:

CASE 1518: A Pilot Trial of Proton Based Cardiac Sparing Accelerated Fractionated RadioTherapy In Unresectable Non-Small Cell Lung Cancer with Extended Durvalumab Therapy (PARTICLE-D). PI: Mitchell Machtay MD, Co-PI: Stephen Shamp MD 

Selected Presentations and Publications:

Stereotactic body radiotherapy (SBRT) for T2N0 (>3 cm) non-small cell lung cancer: Outcomes and failure patterns, Shamp S., Sheikh S., Chang T., Damico N., Linden P., Dowlati A., Machtay M., Biswas T, Journal of Radiosurgery and SBRT, 2021 

Radiation Therapy Is Associated with Improved Overall Survival in Non-Metastatic Merkel Cell Carcinoma: A Surveillance, Epidemiology and End Results (SEER) Analysis. S. Shamp, N. Damico, K. Chaung, M. Kharouta, M. Yao, ASTRO, September 2019

Efficacy of Chemoradiation and Patterns of Practice In The Treatment of Locally Advanced Endometrial Stromal Sarcoma: An NCDB Population-Based Study. M. Kharouta, K. Chaung, S. Shamp,T. Biswas, ASTRO, September 2019

Improved Survival in Patients with High Risk Soft Tissue Sarcomas of the Extremities who receive Radiation and Chemotherapy: An Updated Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database. N. Damico, S. Shamp, A. Wu, P. Getty, A. Mangla, D. Mansur, A. Bhatt, ASTRO, September 2019

Gammaknife Radiosurgery for Small Cell Lung Cancer: Prognostic Factors Including Additional Lesions Identified on the Day of Radiosurgery. K. Chaung, M. Kharouta, S.Shamp, M. Machtay, A. Sloan, A. Bhatt, D. Mansur, T. Hodges, Y. Zhang, S. Choi. Neuro-Oncology Advances, August 2019

Non-Metastatic Inflammatory Breast Cancer: A Surveillance, Epidemiology and End Results (SEER) Analysis, S.Shamp, T. Biswas, ASTRO, October 2018

Post-Mastectomy Radiation Therapy (PMRT) in Women with T3N0 Breast Cancer: An Updated Surveillance, Epidemiology and End Results (SEER) Analysis, N. Damico, S.Shamp, T. Biswas, ASTRO, October 2018

Postoperative Radiotherapy for Stage II or III Non-Small-Cell Lung Cancer: An updated Surveillance, Epidemiology, and End Results Database Study. S. Shamp, N. Damico, M. Machtay, T. Biswas, ASCO, June 2018

Results of Stereotactic Body Radiation Therapy (SBRT) for T2 lung cancer: Suboptimal outcomes with longer term follow-up. S. Shamp, T. Chang, T. Biswas, P. Linden, Y. Perry, J. Kazakov, A. Dowlati, M. Machtay, ASCO, June 2017

Palliative Radiation Therapy in Extensive Stage Small Cell Lung Cancer (ES-SCLC): A Survival, Epidemiology and End Results (SEER) Analysis. S. Shamp, R. Patel, T. Biswas, ASTRO, September 2017

Are We Doing Enough? Examining the Failure Pattern Post-SBRT in T2N0 Non–small Cell Lung Cancer Patients: Single Institution Retrospective Review  T. Chang, S. Shamp, T. Biswas, P. Linden, Y. Perry, J. Kazakov, A. Dowlati, M. Machtay, ASTRO, Awarded Top 20 Lung, September 2017 

Practice Locations:

Dr. Shamp's primary practice location is Wellspring Oncology in Pinellas Park, Florida. To schedule an appointment call (727) 343-0600. For more information visit  

Dr. Shamp also treats patients at St. Anthony's Hospital in St. Petersburg, Florida, and has hospital privileges at Bayfront Medical Center, St. Petersburg General Hospital, Largo Medical Center, Northside Hospital, and Palms of Pasadena Hospital.